| Single Game Records - Single Season Records - Career Leaders |
| Single Game Passing Records |
| Leader | 2nd | 3rd | |
| Touchdowns | 8 Jeff Blake  1993 : Week 7 |
7 Drew Brees  2002 : Week 15 |
7 Yoshitaka Eiji  2022 : Week 16 |
| Yards | 459 Andre Ware  1998 : Week 15 |
446 Elvis Grbac  1996 : Week 13 |
428 Tony Banks  2003 : Week 15 |
| Completions | 21 Troy Smith  2007 : Week 16 |
21 Colt McCoy  2011 : Week 15 |
19 Jeff Blake 1994 : Week 5 |
| Attempts | 36 Troy Smith 2007 : Week 16 |
36 Yoshitaka Eiji 2024 : Week 13 |
35 Blaine Gabbert  2017 : Week 9 |
| Interceptions Thrown | 8 Donnie Reed  2019 : Week 10 |
6 Elvis Grbac 1998 : Week 16 |
6 Tommy Maddox  1993 : Week 6 |
