| Rd.Pick | Team | Draftee |
| 1.1 |  Arizona Cardinals (thru TEN. thru K.C.) | RB Steven Jackson |
| 1.2 |  New York Giants (thru PHI.) | WR Larry Fitzgerald |
| 1.3 |  Seattle Seahawks (thru ) | QB Philip Rivers |
| 1.4 | Arizona Cardinals | QB Eli Manning |
| 1.5 |  Kansas City Chiefs (thru DAL.) | QB Ben Roethlisberger |
| 1.6 |  San Francisco 49ers | LB Jonathan Vilma |
| 1.7 | Arizona Cardinals (thru K.C. thru DEN.) | DB Sean Taylor |
| 1.8 |  Dallas Cowboys (thru K.C. thru GIA. thru ) | DB Chris Gamble |
| 1.9 |  New York Jets | LB D.J. Williams |
| 1.10 |  New Orleans Saints | DB DeAngelo Hall |
| 1.11 |  Detroit Lions (thru ARZ. thru K.C. thru DET.) | WR Lee Evans |
| 1.12 | Detroit Lions (thru PIT.) | QB Matt Schaub |
| 1.13 |  Denver Broncos (thru K.C. thru S.F. thru RAI.) | RB Michael Turner |
| 1.14 | Denver Broncos (thru DET. thru CIN.) | DL Jared Allen |
| 1.15 | Seattle Seahawks | DB Nathan Vasher |
| 1.16 |  Washington Redskins | WR Wes Welker |
| 1.17 |  Tennessee Titans | TE Kellen Winslow |
| 1.18 | Kansas City Chiefs (thru S.F. thru RAI. thru GIA.) | LB Karlos Dansby |
| 1.19 | Seattle Seahawks (thru DET. thru BUF.) | DB Dunta Robinson |
| 1.20 |  San Diego Chargers | RB Willie Parker |
| 2.1 | San Francisco 49ers (thru DET. thru DEN. thru ARZ.) | WR Roy Williams |
| 2.2 | Dallas Cowboys | TE Chris Cooley |
| 2.3 | New York Giants (thru RAI. thru S.F.) | K Nate Kaeding |
| 2.4 | Detroit Lions (thru K.C. thru SEA. thru K.C.) | DB Madieu Williams |
| 2.5 |  Philadelphia Eagles | DB Bob Sanders |
| 2.7 | Denver Broncos | OL Nick Hardwick |
| 2.9 | Denver Broncos (thru DET. thru N.O.) | DB Erik Coleman |
| 2.10 | New York Jets | OL Chris Snee |
| 2.11 | New York Giants (thru DET. thru thru PIT.) | LB Daryl Smith |
| 2.12 | Dallas Cowboys (thru CIN. thru DET.) | DL Darnell Dockett |
| 2.13 | Philadelphia Eagles (thru GIA. thru RAI.) | WR Jerricho Cotchery |
| 2.14 |  Cincinnati Bengals | OL Shawn Andrews |
| 2.15 | Seattle Seahawks | OL Max Starks |
| 2.16 | Denver Broncos (thru WAS.) | DB Gibril Wilson |
| 2.17 | Tennessee Titans | RB Kevin Jones |
| 2.18 |  Los Angeles Raiders (thru GIA.) | QB JP Losman |
| 2.19 |  Buffalo Bills | DL Shaun Phillips |
| 2.20 | Seattle Seahawks (thru DET. thru GIA. thru S.D.) | RB Julius Jones |
| 3.1 | Cincinnati Bengals (thru ARZ.) | DB Sean Jones |
| 3.2 | Dallas Cowboys | DB Michael Boulware |
| 3.3 | San Francisco 49ers | TE Ben Watson |
| 3.4 | Los Angeles Raiders (thru K.C. thru ARZ. thru K.C.) | LB Landon Johnson |
| 3.5 | Philadelphia Eagles | LB Demorrio Williams |
| 3.7 | Denver Broncos | WR Devery Henderson |
| 3.8 | Buffalo Bills (thru ) | RB Mewelde Moore |
| 3.9 | New Orleans Saints | OL Robert Gallery |
| 3.10 | New York Jets | DB Stuart Schweigert |
| 3.11 |  Pittsburgh Steelers | OL Jake Grove |
| 3.12 | Philadelphia Eagles (thru DET. thru K.C. thru DET.) | DL Vince Wilfork |
| 3.13 | Detroit Lions (thru GIA. thru DET. thru RAI.) | DL Will Smith |
| 3.14 | Dallas Cowboys (thru CIN.) | DL Tommie Harris |
| 3.15 | San Diego Chargers (thru GIA. thru SEA.) | DB Jacques Reeves |
| 3.16 | Washington Redskins | OL Ryan Lilja |
| 3.18 | Seattle Seahawks (thru K.C. thru GIA.) | RB Greg Jones |
| 3.19 | Buffalo Bills | WR Michael Clayton |
| 3.20 | New York Giants (thru S.D.) | WR Patrick Crayton |
| 4.1 | Buffalo Bills (thru ARZ. thru K.C. thru ARZ.) | LB Teddy Lehman |
| 4.2 | Dallas Cowboys | DB Jason David |
| 4.3 | San Francisco 49ers | DL Antwan Odom |
| 4.4 | Pittsburgh Steelers (thru thru K.C.) | OL Justin Smiley |
| 4.5 | Philadelphia Eagles | DL Tank Johnson |
| 4.7 | Detroit Lions (thru DEN.) | DL Randy Starks |
| 4.9 | New Orleans Saints | DL Robert Geathers |
| 4.10 | New York Jets | DB Jordan Babineaux |
| 4.11 | Pittsburgh Steelers | K Josh Scobee |
| 4.12 | Philadelphia Eagles (thru DET.) | DL Igor Olshansky |
| 4.13 | Los Angeles Raiders | OL Jon Condo |
| 4.14 | Cincinnati Bengals | OL Travelle Wharton |
| 4.15 | Seattle Seahawks | WR Michael Jenkins |
| 4.16 | Washington Redskins | RB Chris Perry |
| 4.17 | Tennessee Titans | DB Shawntae Spencer |
| 4.18 | Detroit Lions (thru GIA. thru K.C. thru GIA.) | LB Brandon Chillar |
| 4.20 | San Diego Chargers | DB Ricardo Colclough |
| 5.1 | Arizona Cardinals | LB Keyaron Fox |
| 5.2 | Dallas Cowboys | DL Kenechi Udeze |
| 5.3 | Dallas Cowboys (thru S.F.) | DB Ahmad Carroll |
| 5.4 | Dallas Cowboys (thru TEN. thru K.C.) | RB Thomas Tapeh |
| 5.5 | Philadelphia Eagles | TE Jeff Dugan |
| 5.6 | New Orleans Saints (thru K.C. thru ) | OL Jake Scott |
| 5.7 | Denver Broncos | DB Will D. Allen |
| 5.9 | New Orleans Saints | OL Jacob Bell |
| 5.10 | New York Jets | LB Alex Lewis |
| 5.11 | Detroit Lions (thru PIT.) | OL Eugene Amano |
| 5.12 | Detroit Lions (thru GIA. thru DET.) | OL Stephen Peterman |
| 5.13 | Los Angeles Raiders | RB Tatum Bell |
| 5.14 | Cincinnati Bengals | DL Bobby McCray |
| 5.15 | New York Giants (thru SEA.) | DL Antonio Smith |
| 5.16 | Dallas Cowboys (thru WAS.) | DL Jason Babin |
| 5.17 | Los Angeles Raiders (thru GIA. thru TEN.) | OL Vernon Carey |
| 5.18 | Los Angeles Raiders (thru GIA.) | WR Ernest Wilford |
| 5.19 | Buffalo Bills | TE Ben Troupe |
| 5.20 | San Diego Chargers | DB Joselio Hanson |
season 35
- Week 19:
DET. 14
-
Harrison GearstR
RB - Buffalo
-
Jeremy MaroneyP
RB - New York
-
Matt MooreR
RB - Cleveland -
Rodney JohnsonR
RB - Cleveland -
Vance McDonaldR
TE - Baltimore -
D.D. ChaneyR
RB - Philadelphia -
Quincy JohnsonR
RB - Los Angeles
Legend:
D = Return Doubtful
Q = Return Questionable
P = Return Probable
R = Returned, Currently Available-
