| Rd.Pick | Team | Draftee |
| 1.1 |  Washington Redskins (thru TEN. thru DET. thru CIN.) | DB Darrelle Revis |
| 1.3 |  Indianapolis Colts (thru WAS.) | RB Adrian L. Peterson |
| 1.5 |  Houston Texans | DB Michael Griffin |
| 1.6 |  Seattle Seahawks | LB Jon Beason |
| 1.8 |  Detroit Lions (thru WAS. thru HOU. thru T.B.) | LB Lamarr Woodley |
| 1.9 | Seattle Seahawks (thru S.F. thru GIA. thru MIN.) | DB Leon Hall |
| 1.10 | Seattle Seahawks (thru DET. thru GIA. thru PIT.) | DB Tanard Jackson |
| 1.11 |  Buffalo Bills | RB Ahmad Bradshaw |
| 1.12 |  New Orleans Saints | WR Dwayne Bowe |
| 1.13 | Seattle Seahawks (thru GIA. thru MIN. thru K.C.) | DB Josh Wilson |
| 1.15 |  New York Jets | OL Joe Thomas |
| 1.16 |  Philadelphia Eagles | WR Steven Smith |
| 1.17 |  Tennessee Titans (thru MIN. thru GIA.) | DB Eric Wright |
| 1.18 | Tennessee Titans | QB Troy Smith |
| 1.19 | Tennessee Titans (thru MIN. thru GIA. thru DET.) | RB Marshawn Lynch |
| 1.20 | Buffalo Bills (thru SEA. thru GIA. thru S.F.) | LB David Harris |
| 2.1 |  New York Giants (thru ) | TE Brent Celek |
| 2.2 | Washington Redskins (thru HOU. thru T.B. thru HOU.) | LB Lawrence Timmons |
| 2.3 | Washington Redskins | WR Mike Sims.Walker |
| 2.4 | Washington Redskins (thru HOU. thru T.B.) | QB Kevin Kolb |
| 2.5 | Seattle Seahawks | OL Ryan Kalil |
| 2.6 | Seattle Seahawks (thru DAL.) | TE Zach Miller |
| 2.7 | Detroit Lions (thru IND.) | LB Paul Posluszny |
| 2.8 | Washington Redskins (thru MIN.) | DB Reggie Nelson |
| 2.9 | New York Giants (thru BUF.) | TE Greg Olsen |
| 2.10 |  Pittsburgh Steelers | WR Steve Breaston |
| 2.11 | Seattle Seahawks (thru CIN.) | RB Pierre Thomas |
| 2.12 | New Orleans Saints | DB Eric Weddle |
| 2.13 | Houston Texans (thru K.C. thru MIN. thru K.C.) | DL Amobi Okoye |
| 2.14 | Seattle Seahawks (thru GIA. thru ) | WR Robert Meachem |
| 2.15 | New York Jets | WR Jacoby Jones |
| 2.16 | Philadelphia Eagles | LB Anthony Spencer |
| 2.17 | Buffalo Bills (thru T.B. thru DET. thru GIA.) | OL Levi Brown |
| 2.18 | Washington Redskins (thru TEN.) | DB Chris Houston |
| 2.19 | Seattle Seahawks (thru GIA. thru HOU. thru DET.) | QB Brady Quinn |
| 2.20 |  San Francisco 49ers | LB Stewart Bradley |
| 3.1 | Detroit Lions (thru ) | RB LeRon McClain |
| 3.2 | Houston Texans | WR James Jones |
| 3.3 | Washington Redskins | WR Legedu Naanee |
| 3.4 |  Dallas Cowboys (thru T.B.) | LB Clint Session |
| 3.5 | Buffalo Bills (thru SEA.) | QB Drew Stanton |
| 3.6 | San Francisco 49ers (thru DAL.) | WR Anthony Gonzalez |
| 3.8 | Detroit Lions (thru MIN. thru DET. thru MIN.) | DB Nedu Ndukwe |
| 3.9 | New Orleans Saints (thru BUF.) | OL Joe Staley |
| 3.10 | Dallas Cowboys (thru PIT.) | OL Ben Grubbs |
| 3.11 | Detroit Lions (thru CIN.) | RB Michael Bush |
| 3.12 | New Orleans Saints | RB Jason Snelling |
| 3.15 | New York Jets | DL Brandon Mebane |
| 3.16 | Philadelphia Eagles | DB Melvin Bullitt |
| 3.17 | Detroit Lions (thru HOU. thru DET. thru GIA.) | LB Zach Diles |
| 3.18 | Tennessee Titans | OL Uche Nwaneri |
| 3.19 |  Kansas City Chiefs (thru GIA. thru DET.) | |
| 3.20 | San Francisco 49ers | LB Prescott Burgess |
| 4.2 | Detroit Lions (thru HOU.) | OL Marshall Yanda |
| 4.3 | Dallas Cowboys (thru WAS. thru DAL. thru WAS.) | DB Kevin Payne |
| 4.4 | Dallas Cowboys (thru T.B.) | WR Ted Ginn |
| 4.5 |  Cincinnati Bengals (thru DAL. thru SEA.) | WR Johnnie Lee Higgins |
| 4.6 | Cincinnati Bengals (thru DAL.) | DB Aaron Ross |
| 4.7 | Indianapolis Colts | DL Gaines Adams |
| 4.8 | Dallas Cowboys (thru TEN. thru MIN.) | TE Kevin Boss |
| 4.9 | Buffalo Bills | LB Quincy Black |
| 4.10 | Washington Redskins (thru PIT.) | OL Justin Blalock |
| 4.11 | Tennessee Titans (thru HOU. thru DET. thru CIN.) | LB Justin Durant |
| 4.12 | New Orleans Saints | WR Chansi Stuckey |
| 4.13 | Tennessee Titans (thru K.C.) | OL Jared Gaither |
| 4.14 | Detroit Lions (thru SEA. thru GIA. thru ) | QB JaMarcus Russell |
| 4.15 | New York Jets | WR Eric Weems |
| 4.16 | New York Jets (thru BUF. thru DAL. thru PHI.) | LB Desmond Bishop |
| 4.17 | Cincinnati Bengals (thru DAL. thru DET. thru GIA.) | LB Stephen Nicholas |
| 4.18 | Tennessee Titans | DB Brandon McDonald |
| 4.19 | New York Giants (thru SEA. thru DET.) | LB Akeem Jordan |
| 4.20 | San Francisco 49ers | QB Trent Edwards |
| 5.2 | Detroit Lions (thru HOU.) | LB Antwan Barnes |
| 5.3 | Cincinnati Bengals (thru GIA. thru WAS.) | LB Brandon Siler |
| 5.4 | New York Giants (thru SEA. thru GIA. thru T.B.) | OL Arron Sears |
| 5.5 | Houston Texans (thru DET. thru SEA.) | OL Doug Free |
| 5.6 | Pittsburgh Steelers (thru WAS. thru DAL.) | OL Tony Ugoh |
| 5.7 | New Orleans Saints (thru DET. thru IND.) | OL Manny Ramirez |
| 5.8 | New Orleans Saints (thru DET. thru MIN.) | OL Mario Henderson |
| 5.9 | Dallas Cowboys (thru BUF.) | DB Dashon Goldson |
| 5.10 | San Francisco 49ers (thru DAL. thru PIT.) | WR Laurent Robinson |
| 5.11 | Cincinnati Bengals | LB Marvin Mitchell |
| 5.12 | New Orleans Saints | QB John Beck |
| 5.13 | New York Giants (thru K.C.) | OL LeRoy Harris |
| 5.15 | New York Jets | LB Will Herring |
| 5.16 | Philadelphia Eagles | RB Garrett Wolfe |
| 5.17 | Detroit Lions (thru DAL. thru K.C. thru GIA.) | RB Brian Leonard |
| 5.19 | Cincinnati Bengals (thru DAL. thru DET.) | LB Tim Shaw |
| 5.20 | San Francisco 49ers | DB Michael Johnson |
season 35
- Week 19:
DET. 14
-
Harrison GearstR
RB - Buffalo
-
Jeremy MaroneyP
RB - New York
-
Rodney JohnsonR
RB - Cleveland -
Matt MooreR
RB - Cleveland -
Vance McDonaldR
TE - Baltimore -
D.D. ChaneyR
RB - Philadelphia -
Quincy JohnsonR
RB - Los Angeles
Legend:
D = Return Doubtful
Q = Return Questionable
P = Return Probable
R = Returned, Currently Available-
