| Rd.Pick | Team | Draftee |
| 1.1 |  Houston Texans (thru DET. thru IND.) | |
| 1.2 |  Philadelphia Eagles (thru TEN. thru BAL.) | QB Jay Cutler |
| 1.3 |  Minnesota Vikings | |
| 1.4 | Houston Texans (thru T.B.) | |
| 1.5 |  Pittsburgh Steelers (thru DET.) | LB DeMeco Ryans |
| 1.6 |  Buffalo Bills | WR Greg Jennings |
| 1.7 | Houston Texans (thru WAS. thru DAL.) | |
| 1.8 |  Detroit Lions (thru TEN. thru S.F.) | LB Chad Greenway |
| 1.9 |  Cleveland Browns (thru DET. thru ) | DB Antonio Cromartie |
| 1.10 |  Seattle Seahawks (thru CLE.) | WR Santonio Holmes |
| 1.11 |  Dallas Cowboys (thru PIT.) | WR Miles Austin |
| 1.12 |  Cincinnati Bengals (thru N.O.) | |
| 1.13 | Houston Texans (thru DET. thru thru CIN.) | |
| 1.14 |  New York Jets | DB Antoine Bethea |
| 1.15 | Dallas Cowboys (thru GIA. thru SEA. thru GIA.) | DB Tramon Williams |
| 1.16 | Philadelphia Eagles | DB Brent Grimes |
| 1.17 | Houston Texans (thru WAS.) | |
| 1.18 | Detroit Lions (thru HOU.) | RB Reggie Bush |
| 1.19 |  Baltimore Ravens (thru TEN.) | |
| 1.20 | Seattle Seahawks (thru GIA. thru SEA.) | QB Vince Young |
| 2.1 | Detroit Lions (thru T.B.) | DB Roman Harper |
| 2.2 | Baltimore Ravens (thru BAL. thru thru BAL.) | |
| 2.3 | Minnesota Vikings | |
| 2.4 |  Indianapolis Colts | DL Mario Williams |
| 2.5 | Seattle Seahawks (thru GIA. thru ) | LB Thomas Howard |
| 2.6 | Dallas Cowboys (thru PIT.) | OL Dbrickashaw Ferguson |
| 2.7 | Indianapolis Colts (thru DET.) | OL Marcus McNeill |
| 2.8 | Houston Texans (thru TEN. thru BAL. thru DAL.) | |
| 2.9 | Dallas Cowboys (thru S.F.) | LB DQwell Jackson |
| 2.10 | Cleveland Browns | DB Johnathan Joseph |
| 2.11 | Buffalo Bills | TE Owen Daniels |
| 2.12 |  New Orleans Saints | DB Michael Huff |
| 2.13 | Detroit Lions (thru SEA. thru CIN.) | LB Ernie Sims |
| 2.14 | New York Jets | DB Bernard Pollard |
| 2.16 | Philadelphia Eagles | TE Tony Scheffler |
| 2.17 |  San Francisco 49ers (thru BAL. thru thru WAS.) | RB Joseph Addai |
| 2.18 | Houston Texans (thru DET. thru HOU.) | |
| 2.19 | Houston Texans (thru thru BAL. thru TEN.) | |
| 2.20 | Seattle Seahawks | OL Jahri Evans |
| 3.1 |  Washington Redskins (thru HOU. thru T.B.) | LB Rocky McIntosh |
| 3.2 | Dallas Cowboys (thru BAL.) | OL Donald Penn |
| 3.3 | Minnesota Vikings | |
| 3.4 | Indianapolis Colts | DB Danieal Manning |
| 3.5 | Dallas Cowboys (thru BAL. thru ) | DL Tamba Hali |
| 3.6 | Pittsburgh Steelers (thru HOU. thru DET. thru PIT.) | TE Marcedes Lewis |
| 3.7 | Dallas Cowboys (thru DET.) | TE Anthony Fasano |
| 3.8 | Seattle Seahawks (thru DAL.) | OL Deuce Lutui |
| 3.9 | San Francisco 49ers | OL Andrew Whitworth |
| 3.10 | Cleveland Browns | QB Matt Leinart |
| 3.11 | Buffalo Bills | DB Cedric Griffin |
| 3.12 | Detroit Lions (thru CIN. thru N.O.) | DL Darryl Tapp |
| 3.13 | Pittsburgh Steelers (thru T.B. thru DET. thru CIN.) | DB Dawan Landry |
| 3.14 | New York Jets | DB Donte Whitner |
| 3.15 | Indianapolis Colts (thru GIA. thru DET. thru GIA.) | K Stephen Gostkowski |
| 3.16 | Baltimore Ravens (thru TEN. thru PHI.) | |
| 3.17 | Washington Redskins (thru BAL. thru WAS.) | RB Leon Washington |
| 3.18 | Detroit Lions (thru HOU. thru T.B. thru HOU.) | RB Jerome Harrison |
| 3.19 | Detroit Lions (thru thru DET. thru TEN.) | DB Jarrad Page |
| 3.20 | New Orleans Saints (thru GIA. thru SEA.) | LB Parys Haralson |
| 4.1 | Detroit Lions (thru T.B.) | TE Delanie Walker |
| 4.2 | Dallas Cowboys (thru DET. thru BAL.) | DB Jason Allen |
| 4.3 | Minnesota Vikings | |
| 4.4 | Indianapolis Colts | OL Willie Colon |
| 4.5 | Dallas Cowboys (thru ) | LB Clint Ingram |
| 4.6 | Pittsburgh Steelers | OL Rob Sims |
| 4.7 | Detroit Lions (thru DAL. thru DET.) | DL Mathias Kiwanuka |
| 4.8 | Cincinnati Bengals (thru DAL.) | |
| 4.9 | San Francisco 49ers | OL Eric Winston |
| 4.10 | Cleveland Browns | WR Jason Avant |
| 4.11 | Buffalo Bills | RB Laurence Maroney |
| 4.12 | New Orleans Saints | LB Brandon Johnson |
| 4.13 | Detroit Lions (thru CIN.) | TE David Thomas |
| 4.14 | New York Jets | DL Kyle Williams |
| 4.15 | Seattle Seahawks (thru DET. thru GIA.) | DL Kamerion Wimbley |
| 4.16 | Philadelphia Eagles | LB Manny Lawson |
| 4.17 | Washington Redskins | OL Winston Justice |
| 4.18 | Houston Texans | |
| 4.19 |  Tennessee Titans | WR Devin Aromashodu |
| 4.20 | Tennessee Titans (thru SEA.) | DB Tim Jennings |
| 5.1 | Detroit Lions (thru GIA. thru T.B.) | OL Chris Kuper |
| 5.2 | Detroit Lions (thru GIA. thru BAL.) | OL Chris Chester |
| 5.3 | Minnesota Vikings | |
| 5.4 | Detroit Lions (thru IND.) | RB Mike Bell |
| 5.5 | New Orleans Saints (thru ) | WR Sinorice Moss |
| 5.6 | Pittsburgh Steelers | WR Maurice Stovall |
| 5.7 | San Francisco 49ers (thru DAL. thru DET.) | OL Charlie Johnson |
| 5.8 | Washington Redskins (thru DAL.) | DB Kelly Jennings |
| 5.9 | Houston Texans (thru TEN. thru S.F.) | |
| 5.10 | Detroit Lions (thru CLE.) | OL Ryan Cook |
| 5.11 | Buffalo Bills | OL Jonathan Scott |
| 5.12 | Minnesota Vikings (thru N.O.) | |
| 5.13 | Cincinnati Bengals | |
| 5.14 | New York Jets | RB LenDale White |
| 5.15 |  Tampa Bay Buccaneers (thru GIA.) | |
| 5.16 | Philadelphia Eagles | WR Ben Obomanu |
| 5.17 | Washington Redskins | DB Ashton Youboty |
| 5.18 | Pittsburgh Steelers (thru DAL. thru HOU.) | QB Bruce Gradkowski |
| 5.19 | Detroit Lions (thru thru TEN.) | WR David Anderson |
| 5.20 | Seattle Seahawks | WR Demetrius Williams |
season 35
- Week 19:
DET. 14
-
Harrison GearstR
RB - Buffalo
-
Jeremy MaroneyP
RB - New York
-
Matt MooreR
RB - Cleveland -
Rodney JohnsonR
RB - Cleveland -
Vance McDonaldR
TE - Baltimore -
D.D. ChaneyR
RB - Philadelphia -
Quincy JohnsonR
RB - Los Angeles
Legend:
D = Return Doubtful
Q = Return Questionable
P = Return Probable
R = Returned, Currently Available-
